Lung function changes after allogenic bone marrow transplantation.

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Lung function changes after allogenic bone marrow transplantation.

The lung function of 21 patients with leukaemia (11 with acute myeloid leukaemia, six with acute lymphatic leukaemia, four with chronic myeloid leukaemia) and of five with severe aplastic anaemia was tested before and after allogenic bone marrow transplantation. Vital capacity (VC) was lowered in patients with leukaemia before transplantation. VC and FEV1 fell significantly after transplantatio...

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ALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA

Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...

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Gonadal function after allogenic bone marrow transplantation for thalassaemia.

Thirty prepubertal patients with thalassaemia major (15 boys and 15 girls) aged from 9.3 to 17.2 years (mean 12.9) who had successfully undergone allogenic bone marrow transplantation were studied. Before the transplant all patients were given short courses of high doses of busulphan (total dose 14 mg/kg) followed by cyclophosphamide (total dose 200 mg/kg). Pituitary gonadal function was assess...

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[Allogenic bone marrow transplantation].

Allogeneic bone marrow transplantation (BMT) after high-dose, marrow-ablative chemoradiotherapy has been established as the treatment of choice for various hematologic, neoplastic, and congenital disorders. The most common type of marrow graft is an allogeneic one from a sibling donor who has compatible human leukocyte antigen (HLA). Only 30% of patients requiring allogeneic BMT have an HLA-com...

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Clearance of severe psoriasis after allogenic bone marrow transplantation.

Case report A 36 year old white man had a 20 year history of severe intractable psoriasis that required numerous admissions to hospital for inpatient treatment. He had long periods of erythrodermic psoriasis and underwent many forms of treatment, including psoralens and ultraviolet A, methotrexate, razoxane, and etretinate, in an attempt to control his psoriasis. In November 1984 he developed a...

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ژورنال

عنوان ژورنال: Thorax

سال: 1986

ISSN: 0040-6376

DOI: 10.1136/thx.41.7.508